ncRNA basic information
ncRNA ID: MIMAT0000281
ncRNA Database: miRBase
ncRNA Name: miR-224-5p
ncRNA Type: miRNA
ncRNA Expression: up-regulated
ncRNA Method: qRT-PCR
ncRNA Target Gene: PRKCD
ncRNA Pathway: PRKCD pathway
Evidence (ncRNA-drug): validated
drug basic information
Drug ID: DB00515 (APRD00359)
Drug Name: Cisplatin
Drug Method: The expression levels of miRNA were determined by qRT-PCR and those of protein were by Western blot analysis. Cellular apoptosis assay by assessing the activation of caspase-3 and -7, and with TUNEL . Computational approaches were used to analyze target prediction of miRNAs .
Drug Response: resistant
Cancer basic information
Cancer: ovarian papillary serous carcinoma
Tissue/Cell: tissue and cell line (A2780CP/A2780S, C13/OV2008)
Other information
Title: Expression of miR-224-5p is associated with the original cisplatin resistance of ovarian papillary serous carcinoma.
Journal: Oncol Rep
Published: 2014
PubMed ID: 25017423