ncRNA basic information
ncRNA ID:
MIMAT0000242
ncRNA Database:
miRBase
ncRNA Name:
miR-129-5p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
ABCB1, ABCC5 and ABCG1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00541 (APRD00495)
Drug Name:
Vincristine
Drug Method:
The role of miR-129-5p in gastric cancer cells was detected using intracellular ADR intensity analysis, in vitro drug sensitivity assay, in vivo drug sensitivity assay, Real-time PCR, western blot and immunohistochemistry, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
cell line (SGC7901,SGC7901/VCR,SGC7901/ADR,SGC7901-Luc )
Other information
Title:
Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters.
Journal:
Oncotarget
Published:
2014
PubMed ID:
25344911