ncRNA basic information
ncRNA ID:
MI0000790
ncRNA Database:
miRBase
ncRNA Name:
miR-382
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
KLF12 and HIPK3
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The expression levels of miRNA were determined by Real-time quantitative PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. Animal experiments was uesed to test the role of miR-382 .
Drug Response:
resistant
Cancer basic information
Cancer:
osteosarcoma
Tissue/Cell:
cell line (MNNG/HOS, U2OS, MG63)
Other information
Title:
miR-382 inhibits tumor growth and enhance chemosensitivity in osteosarcoma.
Journal:
Oncotarget
Published:
2014
PubMed ID:
25344865