ncRNA basic information
ncRNA ID:
MI0000102
ncRNA Database:
miRBase
ncRNA Name:
miR-100
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
FGFR3
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-100 in pancreatic cancer cells was detected using quantitative real-time reverse transcription-PCR (qRT-PCR), cell proliferation assay, luciferase reporter assays and transfection of siRNA, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
pancreatic cancer
Tissue/Cell:
tissue and cell line (AsPC1,BxPc-3, Capan-1, Capan-2, CFPAC-1, PANC-1, MIA, PaCa-2, and SW1990)
Other information
Title:
MicroRNA-100 regulates pancreatic cancer cells growth and sensitivity to chemotherapy through targeting FGFR3.
Journal:
Tumour Biol
Published:
2014
PubMed ID:
25344675