ncRNA basic information
ncRNA ID:
MIMAT0000459
ncRNA Database:
miRBase
ncRNA Name:
miR-193a-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
SRSF2,PLAU and HIC2
ncRNA Pathway:
DNA damage, Notch, NF-kappaB, Myc/Max, and Oxidative Stress
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB01229 (APRD00259, DB05261, DB05927, DB05526, DB05281)
Drug Name:
Paclitaxel
Drug Method:
The role of miR-193a-3p in bladder cancer cells was detected using luciferase reporter assay, real-time PCR, western blotting, BSP analysis, bioinformatics analysis and the in vivo studies, etc.
Drug Response:
resistant
Cancer basic information
Cancer:
bladder cancer
Tissue/Cell:
cell line (EJ,T24,5637,H-bc,Biu87)
Other information
Title:
The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of bladder cancer via repression of SRSF2/PLAU/HIC2 expression.
Journal:
Cell Death Dis
Published:
2014
PubMed ID:
25188512