ncRNA basic information
ncRNA ID:
MI0000342
ncRNA Database:
miRBase
ncRNA Name:
miR-200b
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
NA
Drug Name:
Celastrol
Drug Method:
The expression levels of miRNA were determined by Quantitative Real Time PCR (qRT-PCR) and those of protein were by Western blot analysis. Caspase-3 activation status was measured using the Caspase-Glo 3 Assay . Cell migration was detected by migration and invasion assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
melanoma
Tissue/Cell:
cell line (SNU387/SNU387R or Malme3M/Malme3MR)
Other information
Title:
miR-326-histone deacetylase-3 feedback loop regulates the invasion and tumorigenic and angiogenic response to anti-cancer drugs.
Journal:
J Biol Chem
Published:
2014
PubMed ID:
25138213