ncRNA basic information
ncRNA ID:
MIMAT0002833
ncRNA Database:
miRBase
ncRNA Name:
miR-520a-5p
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
STAT3
ncRNA Pathway:
JAK/STAT signaling pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB06774 (DB05674, DB05318)
Drug Name:
Capsaicin
Drug Method:
The role of miR-520a-5p in chronic myelogenous leukemia cells was detected using cell proliferation assay, qRT-PCR, transient transfection, western blot, apoptosis assay, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
chronic myeloid leukemia
Tissue/Cell:
cell line (K562)
Other information
Title:
MicroRNA-520a-5p displays a therapeutic effect upon chronic myelogenous leukemia cells by targeting STAT3 and enhances the anticarcinogenic role of capsaicin.
Journal:
Tumour Biol
Published:
2014
PubMed ID:
24870597