ncRNA basic information
ncRNA ID:
MI0003124
ncRNA Database:
miRBase
ncRNA Name:
miR-489
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
SMAD3
ncRNA Pathway:
epithelial mesenchymal transition pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Adriamycin
Drug Method:
The role of miR-489 in breast cancer cells was detected using quantitative real-time PCR, western blot, immunofluorescence staining, migration assays, xenograft tumors, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7/WT,MCF-7/ADM)
Other information
Title:
MiR-489 regulates chemoresistance in breast cancer via epithelial mesenchymal transition pathway.
Journal:
FEBS Lett
Published:
2014
PubMed ID:
24786471